Edward Grimley Selected Research

Proteins (Proteins, Gene)

1/2022	Identification of Pax protein inhibitors that suppress target gene expression and cancer cell proliferation.
1/2019	High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds.
1/2018	Are Pax proteins potential therapeutic targets in kidney disease and cancer?
1/2017	The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice.
1/2017	Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain.

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Edward Grimley Research Topics

Disease

8	Neoplasms (Cancer) 01/2022 - 01/2017
4	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 10/2018
1	Polyploidy 01/2022
1	Fibrosis (Cirrhosis) 01/2019
1	Kidney Neoplasms (Kidney Cancer) 01/2018
1	Kidney Diseases (Kidney Disease) 01/2018
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2018
1	Obesity 01/2017
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2017
4	Aldehyde DehydrogenaseIBA 02/2021 - 10/2018
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2021
2	Protein Isoforms (Isoforms)IBA 02/2021 - 10/2018
2	chordinIBA 01/2019 - 01/2017
1	MTOR InhibitorsIBA 01/2022
1	EnzymesIBA 01/2021
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2021
1	Cisplatin (Platino)FDA LinkGeneric 10/2018

Therapy/Procedure

3	Drug Therapy (Chemotherapy) 02/2021 - 10/2018
1	Therapeutics 01/2022